Results 181 to 190 of about 1,047,812 (348)

No evidence lithium supplementation extends lifespan in male Drosophila melanogaster. [PDF]

Biogerontology
McCracken AW, Garden J, White N, Wigby S.   +3 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Extensions of models for the estimation of mating systems using n independent loci

Heredity, 2002
K. Ritland
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The evolution of mate choice and mating biases

Proceedings of the Royal Society of London. Series B: Biological Sciences, 2003
H. Kokko, R. Brooks, M. Jennions, J. Morley   +3 more
semanticscholar   +1 more source

Pickpocket315 affects male mating behavior in the yellow fever mosquito Aedes aegypti. [PDF]

G3 (Bethesda)
Wyer CAS, Amaro IA, Pitcher S, Ponlawat A, Harrington LC, Wolfner MF, Hollis B, Cator LJ.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Assortative Mating in Animals

American Naturalist, 2013
Yuexin Jiang, D. Bolnick, M. Kirkpatrick
semanticscholar   +1 more source

Application of optimal contribution selection, trait distribution management, and group selection in layer chickens. [PDF]

Genet Sel Evol
Wolc A, Kinghorn BP, Kinghorn AJ, Dekkers JCM.   +3 more
europepmc   +1 more source