Results 81 to 90 of about 279,481 (266)

Resilience to ghosting? A randomized controlled trial examining the consequences of ghosting on sleep quality in potential romantic relationships

Frontiers in Psychology
IntroductionGrounded in belongingness theory, the goal of this study is to understand the consequences of ghosting (an approach to ending relationships that involves ending all forms of communication with someone without explanation) on objective and ...
Michael R. Langlais, Anabelen Pons, Olivia Dechert, Anna M. Murvich, Jeremy A. Bigalke   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Morphometry and Morphology of the Body and External Genitalia of Triatoma dimidiata (Hemiptera: Reduviidae) Morphotypes

Taxonomy
In Yucatán state, Mexico, Triatoma dimidiata (Latreille, 1811) is the primary vector of Trypanosoma cruzi, the parasite that causes Chagas disease. The vector population presents diverse forms and colorations.
Karla Y. Acosta-Viana, Carlos M. Baak-Baak, Julio C. Tzuc-Dzul, Isabel Y. Chel-Muñoz, José I. Chan-Pérez, Wilbert A. Chi-Chim, Julian E. Garcia-Rejon, Frida Álvarez-León, Irving May-Concha, Angélica Pech-May, Nohemi Cigarroa-Toledo   +10 more
doaj   +1 more source

Aspects of Ultrasonographic Diagnostics of Pregnancy in Bitches depending on the first mating [PDF]

Veterinary World, 2008
The aim of the present study was to follow up the potential of routine ultrasonographic diagnostics of pregnancy in bitches depending on the first mating. The experiments were performed on 32 bitches.
Aissi, A.
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Impact of diverse musical genres on blood-feeding and mating behavior in Aedes aegypti mosquitoes

Journal of Vector Borne Diseases
Background & objectives: Sound plays an important role in mosquito foraging and sexual interactions. Mosquitoes utilize acoustic signals for host location, sexual recognition, and mating, which is achieved through the rhythmic beating of their wings to ...
Chew Yan Ni, Nur Faeza Abu Kassim, Noor Moukhni Ayub, Sara Abdelrahman Abuelmaali, Abadi M. Mashlawi, Hamady Dieng   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Juvenile hormone regulates the maturation of sexually dimorphic naive ethanol olfactory preference in Drosophila melanogaster

Royal Society Open Science
The molecular mechanisms underlying the maturation of innate reward behaviours remain poorly understood. We have identified a sexually dimorphic innate reward behaviour in Drosophila melanogaster that varies depending on the age, sex and mating status in
Antonio Marini-Davis, Ryan Oliver, Bailey Godwin, Sera Chase, Ziam Khan, Fernando J. Vonhoff   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source