Results 241 to 250 of about 17,602,067 (294)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source
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Mating Systems

2021
This chapter looks into the evolution of mating systems, which relate to social associations and the number of sexual partners of an animal during a breeding season. It explains how animals showcase different mating systems and their selection of mates to maximize their fitness.
Shawn E. Nordell, Thomas J. Valone
openaire   +2 more sources

Mating systems in birds

Current Biology, 2022
Most vertebrates, including all mammals and birds, are sexually reproducing organisms. The implication of sexual reproduction is that an adult bird exists because a male transferred sperm to the reproductive tract of a female during copulation, one of the sperm fertilized an egg, and the ensuing embryo developed into an individual male or female that ...
openaire   +3 more sources

Impact of mating systems on patterns of sequence polymorphism in flowering plants [PDF]

open access: yesProceedings of the Royal Society B: Biological Sciences, 2006
A fundamental challenge in population genetics and molecular evolution is to understand the forces shaping the patterns of genetic diversity within and among species.
Sylvain Glémin   +2 more
exaly   +2 more sources

Modeling Mate Choice in Monogamous Mating Systems with Courtship

Adaptive Behavior, 2002
We present a conceptual framework for the study of mate choice in monogamous mating systems with non-negligible courtship time. Within this framework, we develop a mate choice model for the common case where individuals have a changing social network of potential partners.
Simão, J., Todd, P.
openaire   +2 more sources

Mating Systems

2001
The study of mating is one of the most active areas in evolutionary ecology. What fuels this research is curiosity about a stunning diversity of ways in which zygotes are formed. Many plants and some animals can reproduce without combining gametes. Many other plants combine gametes but do so within the same individual (selfing).
Ann K. Sakai, David F. Westneat
openaire   +2 more sources

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