Results 31 to 40 of about 1,227,610 (324)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Comparison and Implementation of a Rigid and a Flexible Multibody Planetary Gearbox Model [PDF]
Modeling, Identification and Control, 2014 We propose algorithms for developing (1) a rigid (constrained) and (2) a flexible planetary gearbox model. The two methods are compared against each other and advantages/disadvantages of each method are discussed.
Martin Felix Jørgensen +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Matlab code for Lyapunov exponents of fractional order systems
, 2018 In this paper the Benettin-Wolf algorithm to determine all Lyapunov exponents for a class of fractional-order systems modeled by Caputo's derivative and the corresponding Matlab code are presented.
Danca, Marius-F., Kuznetsov, Nikolay
core +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Фізико-математична освітаФормулювання проблеми. Формування навичок застосування класичних математичних інструментів при розв’язанні реальних проблем є однією із задач викладання математичних дисциплін у ЗВО та ВВНЗ. Це вимагає постійного поповнення бази сучасних прикладних задач.
Галина Бобрицька +1 more
doaj +1 more source
Direct Adaption Methods for Linear and Circular Antenna Arrays
Известия высших учебных заведений России: Радиоэлектроника, 2023 Introduction. The mitigation of interferences that degrade the performance of navigation systems constitutes one of the most significant problems of contemporary satellite navigation.
Ye. I. Glushankov, V. I. Tsarik
doaj +1 more source
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source