Results 21 to 30 of about 3,865 (171)

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

Angewandte Chemie International Edition, EarlyView.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo, Kathleen Abt, Konrad Viehrig, Peter J. Jervis, Teresa P. Martins, Iñaki Lacomba, Chuhan Li, Daniele Castagnolo, Pedro N. Leão   +8 more
wiley   +1 more source

Sociodemographic and psychological characteristics influencing patients’ willingness to participate in clinical trials

BMJ Open Quality, 2022
Background/Aims Clinical trials are fundamental for the development of new medicines and patient participation is based on free consent. Our study sought to identify psychological characteristics that may influence patient willingness to participate in a
Vitor Tedim Cruz, Luis Almeida, Rita Gouveia   +2 more
doaj   +1 more source

When Sustainability Reporting Becomes a Strategy: The Impact of Financial Performance and Institutional Pressures From EU Sustainability Reporting Regulations on ESG Decoupling

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Mitigating environmental, social, and governance (ESG) decoupling is essential to advancing reliable sustainability disclosure and ensuring that ESG reporting fulfills its intended purpose. This study aims to provide critical insights into the organizational and contextual elements that could intensify or diminish ESG decoupling. Using a multi‐
Catarina Cepêda, Albertina Paula Monteiro, Cristina Aibar‐Guzmán   +2 more
wiley   +1 more source

Disclosing the production of fungal chitinases and proteases using insect by‐products as substrates in solid‐state fermentation

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The world population is projected to reach nearly 9.7 billion by 2050, significantly increasing the demand for novel and sustainable protein sources. Edible insects, such as Tenebrio molitor, emerge as promising alternatives due to their high nutritional value, but adult insects and frass are direct and abundant by‐products of this ...
Borja Fernández, Helena Fernandes, Nuno Muñoz‐Seijas, Francisco Soto‐Beltrán, José Manuel Domínguez, Helena Peres, José Manuel Salgado   +6 more
wiley   +1 more source

Open letter: Brazil at a crossroads—Protecting peatlands is essential for post‐COP30 climate leadership

PLANTS, PEOPLE, PLANET, EarlyView.
This Open Letter highlights peatlands as critical yet overlooked ecosystems in Brazil's climate and biodiversity policies. By translating scientific evidence into clear, actionable priorities for policymakers, it supports more accurate climate reporting, effective mitigation strategies, and improved land‐use governance.
Suelma Ribeiro Silva, Alexandre Christofaro Silva, Uidemar Morais Barral, Carlos Moreira de Souza Jr, Renato Ramos Silva, Bruno Machado Teles Walter, Franziska Tanneberger, Geraldo Wilson Fernandes, Alexsander Araujo de Azevedo, Ana Cristina Rodrigues Lacerda, André Rodrigo Rech, Angela‐Gallego Sala, Ani Cátia Giotto, Antonio Martínez Cortizas, Barbara Pereira Christofaro Silva, Carlos Eduardo Pellegrino Cerri, Carlos Victor Mendonça Filho, Caroline Signori Müller, Cássia Beatriz Rodrigues Munhoz, Cátia Nunes da Cunha, Chesterton Ulysses Orlando Eugênio, Cristiano Christofaro Matosinhos, Danielle Piuzana Mucida, Danilo Barbuena, Diego Tassinari, Douglas Sathler dos Reis, Eneida Maria Eskinazi Sant'Anna, Esteban Terneus Jácome, Fabiane Nepomuceno Costa, Felix Beer, Guilherme Braga Ferreira, Hans Joosten, Helga Correa Wiederhecker, Ingrid Horák Terra, Jan Peters, João Bernardo de A. Bringel Jr, Kristell Hergoualc'h, Letícia Cândida Pataca, Lucia Maria Porto de Paula, Luciana de Mendonça Galvão, Maiby Glorize da Silva Bandeira, Marcelino Santos de Morais, Marcelo Brilhante de Medeiros, Matheus Kuchenbecker, Natália Rodrigues Bijos, Pablo Vidal Torrado, Patricia Roeser, Ricardo da Silva Carvalho, Rodolfo Iturraspe, Thamyres Sabrina Gonçalves, Thiago Almeida Andrade Pinto, Wilbor Poletti, Yule Roberta Ferreira Nunes   +52 more
wiley   +1 more source

Referenciação aos Cuidados de Saúde Secundários Através de um Processo Informatizado.

Revista Portuguesa de Medicina Geral e Familiar, 2019
Objetivos: Em 2003, um estudo realizado em Matosinhos, previamente à informatização do sistema, determinou uma taxa de referenciação hospitalar de 10,1%, com referenciações maioritariamente de qualidade média, e um tempo médio para a marcação de ...
Hugo Rocha, Raquel Braga, Carla Silva, Sílvia Colmonero Martins, Sofia Faria   +4 more
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

Acta Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco, Nisa Silva, Camiel J. F. Boon   +2 more
wiley   +1 more source

Avaliação do Conhecimento dos Médicos e das Práticas de Seguimento de Doentes com Síndrome de Apneia Obstrutiva do Sono sob Ventiloterapia nos Cuidados de Saúde Primários

Gazeta Médica
INTRODUÇÃO: A síndrome de apneia obstrutiva do sono (SAOS) é uma doença crónica associada a importante morbimortalidade. Com este estudo pretende-se avaliar o seguimento dos doentes com SAOS sob ventiloterapia nos Cuidados de Saúde Primários (CSP) e o ...
Inês Freitas, Leonor Carrapatoso, Cecília Fernandes Vieira, Bárbara Seabra   +3 more
doaj   +1 more source

High School GPA and Exam Scores: Does Their Relevance for First‐Year Academic Performance Vary With Program Selectivity?

Bulletin of Economic Research, EarlyView.
ABSTRACT This paper examines student admissions to higher education based on past performance, focusing on two measures: high school GPA and national exam scores. GPA is teacher‐assigned and based on repeated assessments, while these exams are externally graded, one‐off standardized tests. Using a nationwide dataset, we investigate how the relevance of
Pedro Luis Silva, Carla Sá, Ricardo Biscaia   +2 more
wiley   +1 more source

Palliative needs in a list of users of a family health unit from an urban center

Millenium
Introduction: The Portuguese population is aging, and palliative needs are expected to increase. One of the barriers to timely access to a palliative care approach is the difficulty in identifying patients who could benefit from them. Most patients with
Diana Pacheco, Eliana Frias, Teresa Carneiro, Ilda Gonçalves, Céu Rocha, Liliana Silva   +5 more
doaj   +1 more source