Results 81 to 90 of about 1,002,910 (222)

ادارة المحفظة الاستثمارية المثلى بحث تطبيقي في شركات القطاع الصناعي العراقي الخاص

open access: yesمجلة الغري للعلوم الاقتصادية والادارية, 2017
المستخلص استهدف البحث تحدید المحفظة الاستثماریة المثلى في سوق الع ا رق للأوا رق المالیة، وقد غطى البحث مدة واختیرت عینة البحث من مجتمعها المتمثل في الشركات المساهمة الخاصة المدرجة «2012-2008» زمنیة من شركة عاملة في السوق المالي الع ا رقي للقطاع الصناعي «
جليل كاظم العارضي   +1 more
doaj   +1 more source

Algorithms for ℓp Low Rank Approximation [PDF]

open access: yes, 2017
We consider the problem of approximating a given matrix by a low-rank matrix so as to minimize the entry-wise ℓp-approximation error, for any P ≥ 1; the case p = 2 is the classical SVD problem.
Chierichetti, Flavio   +5 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

On the issue of evaluating the effectiveness of supervision in the Russian financial market

open access: yesИнтеллект. Инновации. Инвестиции, 2019
The modern challenges and realities of development of the domestic financial market are required the presence of a normatively-fixed method of evaluating the effectiveness of the measures and the tools which implemented by the mega-regulator in the ...
L.V. Soldatenkova
doaj   +1 more source

Lagrangian Relaxation and Partial Cover

open access: yes, 2007
Lagrangian relaxation has been used extensively in the design of approximation algorithms. This paper studies its strengths and limitations when applied to Partial Cover.Comment: 20 pages, extended abstract appeared in STACS ...
Mestre, Julián
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Resilience analytics: coverage and robustness in multi-modal transportation networks

open access: yesEPJ Data Science, 2018
A multi-modal transportation system of a city can be modeled as a multiplex network with different layers corresponding to different transportation modes.
Abdelkader Baggag   +3 more
doaj   +1 more source

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