Results 151 to 160 of about 1,376,709 (310)
Psychiatric comorbidity in the Baltimore ECA follow-up study: the matrix approach. [PDF]
Soc Psychiatry Psychiatr Epidemiol, 2023 Miozzo R +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Multi-Matrix Approach for the Analysis of Bicalutamide Residues in Oncology Centers by HPLC-FLD. [PDF]
Molecules, 2021 Portilha-Cunha MF +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Using underapproximations for sparse nonnegative matrix factorization [PDF]
Nonnegative Matrix Factorization (NMF) has gathered a lot of attention in the last decade and has been successfully applied in numerous applications.
GILLIS, Nicolas, GLINEUR, François
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Utilizing a Matrix Approach to Analyze Qualitative Longitudinal Research: A Case Example During the COVID-19 Pandemic. [PDF]
Int J Qual Methods, 2022 Terzis LD +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
New computational approach for the design of fault detection and isolation filters [PDF]
, 2003 We propose a numerically reliable computational approach for the design of residual generators for fault detection and isolation filters. The new approach is based on computing solutions of least dynamical orders of linear equations with rational matrix ...
Varga, Andras
core
Dynamic Stiffness Matrix Approach to Free Vibration Analysis of Functionally Graded Rotor Bearing System Subjected to Thermal Gradients. [PDF]
Materials (Basel), 2022 Obalareddy B, Sathujoda P, Citarella R.
europepmc +1 more source