ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Density-matrix renormalization study of the frustrated fermions on the triangular lattice
, 2009 We show that the two-dimensional density-matrix renormalization analysis is useful to detect the symmetry breaking in the fermionic model on a triangular lattice.
Hotta, C., Nishimoto, S.
core +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
What chemical species are responsible for new particle formation and growth in the Netherlands? A hybrid positive matrix factorization (PMF) analysis using aerosol composition (ACSM) and size (SMPS) [PDF]
, 2023 Farhan R. Nursanto +7 more
openalex +2 more sources
Physicochemical properties of new cellulosic fiber extracted from Carica papaya bark
Journal of Natural Fibers, 2019 This article presents the characteristics of Carica papaya fibers (CPFs) extracted from the bark of the perennial papaya plant. Detailed chemical compositions of CPFs such as cellulose, lignin, ash, moisture, and wax contents were established and ...
A Saravana Kumaar +4 more
doaj +1 more source
Excitation–Emission Matrix Spectroscopy for Analysis of Chemical Composition of Combustion Generated Particulate Matter [PDF]
, 2020 Gaurav Mahamuni +7 more
openalex +1 more source
Energy, 2015 Abstract This study is for the technoeconomic analysis of an integral facility consisting of wind energy-based electrolytic hydrogen production, bioethanol-based carbon dioxide capture and compression, and direct methanol synthesis. ASPEN Plus was used to simulate the facility producing 97.01 mt (metric tons) methanol/day using 138.37 mt CO 2 /day ...
Michael Matzen +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Compositional data analysis in archaeometry [PDF]
, 2003 We shall call an n × p data matrix fully-compositional if the rows sum to a constant, and sub-compositional if the variables are a subset of a fully-compositional data set1.
Baxter, MJ +3 more
core +1 more source