Results 101 to 110 of about 1,668,606 (328)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Comparative Analysis of Chemical Activators and Expansive Agents for Aeolian Sand Stabilization Using Industrial Solid Waste-Based Geopolymers

open access: yesGels
Aeolian sand is the primary geological material for construction in desert regions, and its stabilization with industrial solid wastes-based geopolymer (ISWG) provides an eco-friendly treatment replacing cement.
Zilu Xie   +4 more
doaj   +1 more source

Density-matrix renormalization study of the frustrated fermions on the triangular lattice

open access: yes, 2009
We show that the two-dimensional density-matrix renormalization analysis is useful to detect the symmetry breaking in the fermionic model on a triangular lattice.
Hotta, C., Nishimoto, S.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Physicochemical properties of new cellulosic fiber extracted from Carica papaya bark

open access: yesJournal of Natural Fibers, 2019
This article presents the characteristics of Carica papaya fibers (CPFs) extracted from the bark of the perennial papaya plant. Detailed chemical compositions of CPFs such as cellulose, lignin, ash, moisture, and wax contents were established and ...
A Saravana Kumaar   +4 more
doaj   +1 more source

Chemical fixation of electroplating sludge and microstructural analysis of stabilised matrix using fly ash and cement

open access: yesMaterials Research Innovations, 2009
AbstractStabilisation and microstructural examination of stabilised electroplating industrial sludge has been studied. Investigations were undertaken to formulate cementitous binder by judicious blending of fly ash, sludge and cement with five mix proportions. The major metallic contaminants were cadmium, chromium, copper, nickel and lead.
Dayananda, H. S.   +2 more
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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