The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
M-MATRIX-WP6.M1 - "DASHBOARDS OPERATIONAL WITHIN THE PILOT PARTICIPATING AGENCIES"
M-MATRIX-WP6.M1 - “Dashboards operational within the pilot participating agencies” Milestone report for M1 of MATRIX ...
MATRIX
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Monolithically Integrated Polarization Mode Convertors with Semiconductor Lasers
Half and full polarization mode convertors which are monolithically integrated with semiconductor lasers are reported. A polarization mode conversion of above 40% and 88% was obtained using single and two back-to-back PMCs ...
Akbar, J. +13 more
core +1 more source
Evaluation of Storage for Transportation Equipment, Unfueled Convertors, and Fueled Convertors at the INL for the Radioisotope Power Systems Program [PDF]
This report contains an evaluation of the storage conditions required for several key components and/or systems of the Radioisotope Power Systems (RPS) Program at the Idaho National Laboratory (INL).
Lively, K. L. +3 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Control of Dual-Opposed Stirling Convertors with Active Power Factor Correction Controllers [PDF]
When using recently-developed active power factor correction (APFC) controllers in power systems comprised of dual-opposed free-piston Stirling convertors, a variety of configurations of the convertors and controller(s) can be considered, with ...
Lewandowski, Edward J. +2 more
core
Avid Convertors in racks.https://repository.belmont.edu/ownphotos/1206/thumbnail ...
Ocean Way Nashville
core +1 more source

