Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Rotary and solid-state frequency convertors for induction heating
, 2012 Předložená práce je zaměřena na indukční ohřev, zejména na rotační a statické mněniče kmitočtu, pro indukční zařízení.Katedra elektromechaniky a výkonové elektronikyObhájenoRotary and solid-state frequency convertors for induction heating This present ...
Řezníček, Oldřich
core
Test Rack Development for Extended Operation of Advanced Stirling Convertors at NASA Glenn Research Center [PDF]
, 2009 The U.S. Department of Energy, Lockheed Martin Space Systems Company, Sunpower Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science missions.
Dugala, Gina M.
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Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi +8 more
wiley +1 more source
Processing and Preparation of Advanced Stirling Convertors for Extended Operation [PDF]
, 2008 The U.S. Department of Energy (DOE), Lockheed Martin Space Company (LMSC), Sunpower Inc., and NASA Glenn Research Center (GRC) have been developing an Advanced Stirling Radioisotope Generator (ASRG) for use as a power system on space science missions ...
Oriti, Salvatore M., Cornell, Paggy A.
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HDR CCD Image Sensor System through Double-A/D Convertors
, 2011 In this paper we present a CCD image sensor system with high dynamic range. This feature is achieved through double analog-to-digital convertors’(ADC) architecture and field programmable gate arrays(FPGA).
Pei Hong Li +3 more
core +1 more source
Reconfigurable nonlinear photonic activation function for photonic neural network based on non-volatile opto-resistive RAM switch. [PDF]
Light Sci Appl, 2022 Xu Z +7 more
europepmc +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin
, 2002 Recent work indicates that cartilage oligomeric matrix protein (COMP) plays an important role in extracellular matrix assembly and matrix-matrix protein interactions.
Leslie, MP +15 more
core +1 more source