Results 71 to 80 of about 815,798 (337)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Self-duality from twisted cohomology

Journal of High Energy Physics
Recently a notion of self-duality for differential equations of maximal cuts was introduced, which states that there should be a basis in which the matrix for an ε-factorised differential equation is persymmetric.
Claude Duhr, Franziska Porkert, Cathrin Semper, Sven F. Stawinski   +3 more
doaj   +1 more source

Matrix-equation-based strategies for convection-diffusion equations

, 2015
We are interested in the numerical solution of nonsymmetric linear systems arising from the discretization of convection-diffusion partial differential equations with separable coefficients and dominant convection.
Palitta, Davide, Simoncini, Valeria
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Interval matrix differential equations

, 2012
The matrix differential equation $x'(t) = Q(t)x(t), x(0) = x_0$ is considered in the case where $Q(t)$ is an unspecified matrix function of time, with the only constraint that $Q(t)\in \mset$ for every $t$, where $\mset$ is a prescribed closed and convex set of matrices.
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Application Backstepping Method for Stabilizing and Solving Delayed Lotaka-Volterra with A Dynamical Graph

Tikrit Journal of Pure Science
The primary goal of this work is to introduce dynamic graphs. Specifically, it will demonstrate that the matrix is the basic matrix of interconnections (adjacency).
Mayadah Khalil Ghaffar, Fadhel S. Fadhel, Nabeel E. Arif   +2 more
doaj   +1 more source

A method of extended normal equations for tikhonov’s regulatization problems with differentiation operator

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014
This article is devoted to a new method of ill-conditioned linear algebraic systems solving with the help of differentiation operator. These problems appear while solving the first kind integral Fredholm equations.
Alexandr I Zhdanov, Ivan A Mikhaylov
doaj   +1 more source

On linear matrix differential equations

Advances in Applied Mathematics, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Monte Carlo Neutrino Oscillations

, 2005
We demonstrate that the effects of matter upon neutrino propagation may be recast as the scattering of the initial neutrino wavefunction. Exchanging the differential, Schrodinger equation for an integral equation for the scattering matrix S permits a ...
Gail C. McLaughlin, H. W. Lilliefors, James P. Kneller, S. P. Mikheyev, S. P. Mikheyev, W. H. Press   +5 more
core   +1 more source