Results 141 to 150 of about 3,510,435 (284)
Analytic trajectory bootstrap for matrix models
We revisit the large N two-matrix model with tr[A, B]2 interaction and quartic potentials by the analytic trajectory bootstrap, where A and B represent the two matrices.
Wenliang Li
doaj +1 more source
Matrix models and deformations of JT gravity. [PDF]
Witten E.
europepmc +1 more source
The contribution of reducible connections to the U(N) Chern-Simons invariant of a Seifert manifold $M$ can be expressed in some cases in terms of matrix integrals.
Garoufalidis, Stavros, Marino, Marcos
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Simulating matrix models with tensor networks
Matrix models, as quantum mechanical systems without explicit spatial dependence, provide valuable insights into higher-dimensional gauge and gravitational theories, especially within the framework of string theory, where they can describe quantum black ...
Enrico M. Brehm +3 more
doaj +1 more source
We show that an integral transform of the fluctuations of the collective field of the d=1 matrix model satisfy the same linearized equation as that of the massless “tachyon” in the black hole background of the two-dimensional critical string. This suggests that the d=1 matrix model may provide a non-perturbative description of black holes in two ...
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Arrangement of Ceramides in the Skin: Sphingosine Chains Localize at a Single Position in Stratum Corneum Lipid Matrix Models. [PDF]
Beddoes CM +7 more
europepmc +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source

