Results 81 to 90 of about 670,467 (323)

Perturbation Bounds of LR Fuzzy Linear Systems

open access: yesFuzzy Information and Engineering
This paper proposes a new method to discuss the perturbation problem of the LR fuzzy linear systems by an embedding method. By solving the perturbation equation of the original fuzzy linear systems, the respective relative error bounds are analyzed and ...
Kun Liu, Xiaobin Guo
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Norms and Spread of the Fibonacci and Lucas RSFMLR Circulant Matrices

open access: yesAbstract and Applied Analysis, 2015
Circulant type matrices have played an important role in networks engineering. In this paper, firstly, some bounds for the norms and spread of Fibonacci row skew first-minus-last right (RSFMLR) circulant matrices and Lucas row skew first-minus-last right
Wenai Xu, Zhaolin Jiang
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

On the matrix norms of a GCD related matrix [PDF]

open access: yesMathematical Inequalities & Applications, 2008
In this paper we investigate the matrix norms of a GCD related matrix, i.e., (S-f) = (f (i,j)/(i(r)j(r))) for multiplicative arithmetical functions f. In particular, we obtain upper bounds for the lp norms of (S-f) for f = phi, sigma alpha and psi in terms of infinite prime products.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Graph regularised sparse NMF factorisation for imagery de‐noising

open access: yesIET Computer Vision, 2018
When utilising non‐negative matrix factorisation (NMF) to decompose a data matrix into the product of two low‐rank matrices with non‐negative entries, the noisy components of data may be introduced into the matrix.
Yixian Fang, Huaxiang Zhang, Yuwei Ren
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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