Results 141 to 150 of about 4,801,130 (303)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Matrix product operator representations

open access: yes, 2008
We show how to construct relevant families of matrix product operators in one and higher dimensions. Those form the building blocks for the numerical simulation methods based on matrix product states and projected entangled pair states. In particular, we
Verstraete, Frank (Quantum Optics, Quantum Nanophysics and Quantum Information, Faculty of Physics, University of Vienna)   +3 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Measurement-induced phase transitions by matrix product states scaling

open access: yesPhysical Review Research
We study the time evolution of long quantum spin chains subjected to continuous monitoring projected on matrix product states (MPS) with fixed bond dimension, by means of the Time-Dependent Variational Principle (TDVP) algorithm.
Guillaume Cecile   +2 more
doaj   +1 more source

A Method for Isomorphism Recognition of Kinematic Chain based on the Hamming Matrix and Connecting Rod Adjacency Matrix

open access: yesJixie chuandong, 2021
In the creative design of mechanical devices,the isomorphic kinematic chains should be eliminated to reduce the mechanism scheme for subsequent design and improve the design efficiency of mechanical device.
Changjun Wu   +4 more
doaj  

A novel approach to product lifecycle management and engineering using behavioural models for the conceptual design phase.

open access: yes
This work builds upon a previous proposal for the use of the extended SAPPhIRE model of causality as a foundation for a PLM system, and more specifically the management of design data at the conceptual design phase.

core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Quantum State Designs with Clifford-Enhanced Matrix Product States

open access: yesPRX Quantum
Nonstabilizerness, or “magic,” is a critical quantum resource that, together with entanglement, characterizes the nonclassical complexity of quantum states.
Guglielmo Lami   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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