Results 141 to 150 of about 4,993,076 (256)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Dot Product Matrix Compression for Machine Learning [PDF]
, 2019 When pairwise dot products are computed between input embedding vectors and the dot product is used for further computation, the number of dot products grows quadratically with the number of embedding vectors.
, Anonymous
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
3D Discrete Matrix-Product Operation and Its Generalization
Journal of Function SpacesTwo-dimensional (2D) discrete matrix-product operation (DMPO) and its corresponding matrix-product neural networks (MPNNs) are the substitutions of 2D discrete convolutional operation and its corresponding convolutional neural networks (CNNs ...
Chuanhui Shan, Hu Li, Chao Han
doaj +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Product Design Based on Matrix Functions and Components
TecnoLógicas, 2013 It’s presented a tool for product design based on the rearrangement of features and components matrix. This tool has been developed in MATLAB and uses a first process based on the diagonalization, a second process based on the exchange of items and ends ...
Oscar E. Herrera-Bedoya +1 more
doaj
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Infinite matrix product states for (1 + 1)-dimensional gauge theories
Journal of High Energy PhysicsWe present a matrix product operator construction that allows us to represent the lattice Hamiltonians of (abelian or non-abelian) gauge theories in a local and manifestly translation-invariant form.
Ross Dempsey +3 more
doaj +1 more source