Results 41 to 50 of about 302,520 (264)

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A New Characterization of Generalized Complementary Basic Matrices

open access: yesSpecial Matrices, 2014
In this paper, a new characterization of previously studied generalized complementary basic matrices is obtained. It is in terms of ranks and structure ranks of submatrices defined by certain diagonal positions.
Fiedler Miroslav, Hall Frank J.
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Cooperative Electromagnetic Data Annotation via Low-Rank Matrix Completion

open access: yesRemote Sensing, 2022
Electromagnetic data annotation is one of the most important steps in many signal processing applications, e.g., radar signal deinterleaving and radar mode analysis.
Wei Zhang   +5 more
doaj   +1 more source

Gaussian Ranking by Matrix Factorization [PDF]

open access: yesProceedings of the 9th ACM Conference on Recommender Systems, 2015
The ranking quality at the top of the list is crucial in many real-world applications of recommender systems. In this paper, we present a novel framework that allows for pointwise as well as listwise training with respect to various ranking metrics. This is based on a training objective function where we assume that, for given a user, the recommender ...
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

All Solutions of the Yang–Baxter-Like Matrix Equation for Nilpotent Matrices of Index Two

open access: yesComplexity, 2020
Let A be a nilpotent matrix of index two, and consider the Yang–Baxter-like matrix equation AXA=XAX. We first obtain a system of matrix equations of smaller sizes to find all the solutions of the original matrix equation.
Duanmei Zhou, Jiawen Ding
doaj   +1 more source

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