Results 91 to 100 of about 9,069,057 (289)

FRONT MATTER

open access: yesJINOP (Jurnal Inovasi Pembelajaran), 2018
FRONT MATTER FRONT MATTER
doaj   +3 more sources

Creatio ex nihilo jako problem kosmologiczny i egzegetyczny?

open access: yesStudia Koszalińsko-Kołobrzeskie
The doctrine creatio ex nihilo is today a fundamental belief in Catholic theology of creation. It is sometimes questioned based on the “current” state of knowledge provided by modern physical cosmology.
Janusz Lemański
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The determination of substantiality and the gradual aspect of natural beings in Aristotle

open access: yesO Que Nos Faz Pensar
In Metaphysics Z3, Aristotle declares that a substance is identified as such, mainly, by having the characteristics of being something separate (χωριστὸν) and of being a certain this (τόδε τι).
Rodrigo Romão de Carvalho
doaj   +1 more source

Constraints on leptophilic dark matter from the AMS-02 experiment

open access: yes, 2017
The annihilation of dark matter particles in the galactic halo of the Milky Way may lead to cosmic ray signatures that can be probed by the AMS-02 experiment, which has measured the composition and fluxes of charged cosmic rays with unprecedented ...
Cavasonza, Leila Ali   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

On the issue of the modern interpretation of the meaning of the concept of «energy» and its properties

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2022
THE PURPOSE. Within the framework of the fourth integral-differential stage of scientific knowledge development, the modern interpretation of matter as a set of mass and energy components, the paradigm of its multilevel organization (fields, substances ...
O. S. Sirotkin, R. O. Sirotkin
doaj  

Gravitational effects of condensate dark matter on compact stellar objects

open access: yes, 2012
We study the gravitational effect of non-self-annihilating dark matter on compact stellar objects. The self-interaction of condensate dark matter can give high accretion rate of dark matter onto stars.
Cheng, K. S., Li, Xinyu, Wang, Fayin
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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