Results 131 to 140 of about 10,032,286 (342)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Transformation of terrestrial organic matter along thermokarst-affected permafrost coasts in the Arctic

, 2017
George Tanski, Hugues Lantuit, Saskia Ruttor, Christian Knoblauch, Boris Radosavljevic, Jens Strauß, Juliane Wolter, Anna Irrgang, Justine Ramage, Michael Fritz   +9 more
openalex   +2 more sources

General relativistic razor-thin disks with magnetically polarized matter [PDF]

, 2018
Anamaría Navarro-Noguera, F. D. Lora-Clavijo, Guillermo A. González   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A “What Matters Most” approach to investigating intersectional stigma toward HIV and cancer in Hanoi, Vietnam [PDF]

Evan L. Eschliman, Dung Hoang Tien, Nasim Khoshnam, Vivian R. Ye, Haruka Kokaze, Yatong Ji, Yining Zhong, Aditi Morumganti, Wenyu Xi, Sijia Huang, Karen Choe, Ohemaa B. Poku, Gloria Guevara Alvarez, Trang Nguyen, Nam Nguyen, Donna Shelley, Lawrence H. Yang   +16 more
openalex   +1 more source

Front Matter: Volume 7865 [PDF]

, 2011
Proceedings of SPIE
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

FRONT MATTER

El Harakah, 2021
Front Matter Front Matter
doaj  

Devotional Tools and Companions to Everyday Life:

Parse Journal
This essay explores the equivalence of various, occasionally contradictory and hybrid perceptions of materiality experienced in physical and non-physical contact.
Agnieszka Patała
doaj