Results 111 to 120 of about 3,001,586 (261)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2009 Freud attempted to explain human behavior, scientifically, as the consequence of the clash between reason and unconscious sexual drives. Rank, whose early work applied psychoanalytic understanding to an analysis of myth, returned to the core of religious
Sturtevant, Peter A., Jr.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Rudolf Steiner and Peter Sellars: Theory to Practice
, 2012 Creativity can be found all around us. It can be witnessed, experienced and overlooked every day. Across the globe and cross culturally, evidence of creativity exist since the beginning of documented time, from ancient Greece to the present.
Di Nolfi, Louis Balestra
core +1 more source
Study of 4-Benzoylbenzoic Acid as a Proxy of Environmental Photosensitizers
, 2021 Sea-spay aerosols (SSA) released from the marine boundary layer (MBL) through wave breaking and bubble bursting contain marine chromophoric dissolved organic matter (m-CDOM). These complex substances can act as photosensitizers of atmospheric trace gases,
Alija, Onita
core
Drawing drupes as a means of development of spatial thinking
Освітній вимір, 2009 In the article typology and receptions of transmission of folds is crammed in the educational raising. The didactics value of picture of draperies as facilities of development of analytical thought of students is investigational.
O.L. Udovenko
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
No Matter How Long the Winter, Spring is Sure to Follow -3
, 2017 https://creativematter.skidmore.edu/altered_books_2017/1012/thumbnail ...
Acee, Lori
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source