Results 61 to 70 of about 2,996,286 (308)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Back Matter Vol. 7 No. 2, 2023

open access: yes, 2023
Back Matter Vol. 7 No.
Back Matter
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Influence of Chronic Illness on Mental Health: Does the Age of the Patient Matter?

open access: yes, 2019
It is no secret that battling a chronic illness can impact an individual’s mental health, all while simultaneously harming their physical health. Although many say that this connection between chronic illness and mental health is obvious, we may still ...
Santostefano, Marianna
core  

BACK MATTER, 6(1), Maret 2021

open access: yes, 2021
Back Matter Volume 6 Nomor 1 Maret ...
MATTER, BACK
core   +1 more source

The Feminine Sacred: An Ontosociology of Woman as a Symbol

open access: yesReligions
In contemporary development, feminism is divided into two major trends, that of difference and that of equality. The former tends to rely more on ontology and religious symbolism, and the latter on sociology and political praxis.
Jacinto Choza
doaj   +1 more source

The criterion of individuation in the philosophy of Aristotle: Form or Matter? [PDF]

open access: yesحکمت و فلسفه, 2015
The discussion of the criterion of individuation has been an important and complex metaphysical debate in the history of philosophy and this is related with what its presence makes us to reach from the general or universal person to the fiddling person ...
mojtaba derayati
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Monodisperse elastic shells: a 3D study of jammed granular matter and microencapsulation

open access: yes, 2014
This thesis focusses on two, admittedly rather different, applications of spherical elastic shells. First in the field of microencapsulation as a smart container to encapsulate and release functional materials.
Sub Soft Condensed Matter   +2 more
core  

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