Results 151 to 160 of about 1,492,362 (344)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
"Occupational asthma": a matter of concern [PDF]
openaire +2 more sources
Coral bleaching - matter of global concern
The destruction of coral reefs is often looked at with a blind eye whereas in reality it could have disastrous consequences for both human and marine life. Coral reefs are considered as one of the most productive ecosystems on the earth, but human activities continue to be the primary cause of the global coral reefs crisis. The first part of this paper
Yadau, Neetika, Priyadarshini, T.
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Overvaluation of shape and weight in adolescents with anorexia nervosa: does shape concern or weight concern matter more for treatment outcome? [PDF]
Catherine E. Byrne +7 more
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Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
"Saying no is no easy matter" A qualitative study of competing concerns in rationing decisions in general practice [PDF]
Benedicte Carlsen, Ole Frithjof Norheim
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We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Sterilization regret in India: Is quality of care a matter of concern? [PDF]
Anjali Bansal, Laxmi Kant Dwivedi
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