Results 81 to 90 of about 1,492,362 (344)

A monstrous matter: The three faces of artificial creativity

open access: yesJournal of Creativity
Through a focus on artificial creativity (AC), creativity and innovation researchers, practitioners, and educators are beginning to demystify the phenomenon's liminality by exploring and contesting the potential affordances, constraints, and pitfalls ...
Robert A. Edgell
doaj   +1 more source

More prayer, more community [PDF]

open access: yes, 2019
This article was originally published in The Prophet -- a journal created by and for the students at the Boston University School of Theology (BUSTH) to amplify the voices of STH students by promoting and sharing a range of perspectives on matters of ...
Johnson, Hazel
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Love lifts above all judgement [PDF]

open access: yes, 2016
This article was originally published in The Prophet -- a journal created by and for the students at the Boston University School of Theology (BUSTH) to amplify the voices of STH students by promoting and sharing a range of perspectives on matters of ...
Lyon, Kelsey
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Robert Walser’s Topicality and the Descriptive Turn

open access: yesOn_Culture, 2019
The article examines the relation between the sudden rise of public interest in the Swiss writer Robert Walser at the turn of the millennium and the simultaneous emergence of Latourian-inspired methodological discussions in the field of literary studies.
Johanne Gormsen Schmidt
doaj  

Unfinished cultural business. A mess-up on sustain, revolts, intuitions, and revolutions [PDF]

open access: yeslo Squaderno, 2009
In as little as the last 5 years or so, conditions have changed for our reflection around the need for change. Of course, this has been prepared over several decades. Yet, today, the idea that we need a deep transformation of some kind is more widespread
Oleg Koefoed
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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