Results 31 to 40 of about 1,970,999 (278)

Does competition between hospitals improve clinical quality?: a review of evidence from two eras of competition in the English NHS [PDF]

open access: yes, 2011
Gwyn Bevan and Matthew Skellern review evidence on the effects of hospital competition on quality of care within the English NHS and question whether they support government proposals to extend ...
Bevan, Gwyn, Skellern, Matthew
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Die plek en funksie van topologie as teologiese belangeruimte in die struktuur van die Matteus-evangelie

open access: yesHTS Teologiese Studies/Theological Studies, 2003
The place and function of topology as theological point of interest in the structure of the Gospel of Matthew This article focuses on the place and function of topology within the structure of Matthew.
G.J. Volschenk
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Die Abraham-motief in Matteus 1-4

open access: yesVerbum et Ecclesia, 1998
The Abraham-motive in Matthew 1-4 Matthew s indication of Jesus as the Son of David and the Son of Abraham develop along two lines in Matthew s story. Firstly, is Jesus portrayed as the Son of David, who represents the Jewish line in the story.
L. Nortj�
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The superior authority of Jesus in Matthew to interpret the Torah

open access: yesIn die Skriflig, 2016
The arguments posed in this article serve to demonstrate the underlying conflict and struggle for authority in the Matthean Gospel. This struggle signifies part of the debate of those days about the trustworthy keepers of the Torah. Whilst Josephus wrote
Francois P. Viljoen
doaj   +1 more source

New Exhibit at the Zoo [PDF]

open access: yes, 2017
Poetry by Matthew Del ...
Del Busto, Matthew
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Intracellular pH Regulates TRAIL-Induced Apoptosis and Necroptosis in Endothelial Cells

open access: yesJournal of Immunology Research, 2017
During ischemia or inflammation of organs, intracellular pH can decrease if acid production exceeds buffering capacity. Thus, the microenvironment can expose parenchymal cells to a reduced extracellular pH which can alter pH-dependent intracellular ...
Zhu-Xu Zhang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy