Results 31 to 40 of about 1,208,525 (273)
Verbum et Ecclesia, 2022 The trinitarian formula of Matthew 28:19: Fremdkörper or an appropriate conclusion? The aim of the article is to investigate whether the trinitarian formula of Matthew 28:19 (‘… baptise them in the name of the Father and of the Son and of the Holy Spirit
Hermias C. van Zyl
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Jesus’ identity in Matthew 16:13–20 and identity crisis among gospel preachers in Nigeria
HTS Teologiese Studies/Theological StudiesThe Jesus’ question which was encased in his shadowy identity was both a fascinating and enigmatic phenomenon to people of Jesus time as well as people of today. The synoptic gospels presented the matter of Jesus identity in varying contexts; however, it
Prince E. Peters +2 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Royal Studies Journal, 2021 Review of Matthew Ward and Matthew Hefferan, eds., Loyalty to the Monarchy in Late Medieval and Early Modern Britain, c.1400–1688 (Palgrave Macmillan, 2020).
Sarah Betts
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
HTS Teologiese Studies/Theological Studies, 2003 The place and function of topology as theological point of interest in the structure of the Gospel of Matthew This article focuses on the place and function of topology within the structure of Matthew.
G.J. Volschenk
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FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source