Results 121 to 130 of about 1,112,622 (261)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Higher capability maturity dynamics of UK construction organisations [PDF]

open access: yes
This paper attempts to identify the dynamics of the CMM (Capability Maturity Model) higher capability maturity level characteristics within the UK construction context from a theoretical perspective.
Amaratunga, Dilanthi   +2 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Orientation in time and world through history and civic education: curricular frameworks and teachers’ perspectives in Austria

open access: yesHistory Education Research Journal
This article explores the connection between historical and political learning as well as their contribution to the promotion of democratic consciousness in Austrian lower secondary education.
doaj   +2 more sources

The At Issue Maturity of Corporate Bonds: The Influence of Credit Rating, Security Level, Duration and Macreoconomic Conditions [PDF]

open access: yes
We examine the determinants of the at issue time to maturity of corporate bonds. We find evidence that corporations partly determine the at issue maturity of bonds by responding to economic conditions.
Frank Skinner, Geetajali Bali
core  

Test Bed project evaluation additional maturity model analyses: technical report 26/07 [PDF]

open access: yes, 2007
Additional analysis: ICT Test Bed evaluation Maturity ...
Dillon, Gayle, Underwood, Jean
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Lung maturation [PDF]

open access: yesProceedings of the Nutrition Society, 1996
R, Hume, C, Conner, M, Gilmour
openaire   +2 more sources

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