Results 71 to 80 of about 229,302 (269)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Geochemical characteristics of crude oil and contributions to hydrocarbon accumulation in multiple stages in Tahe subsalt area

Shiyou shiyan dizhi
The process of hydrocarbon accumulation in polycyclic superimposed basins often involves multistage crude oil charging, but not every stage of crude oil charging plays a significant role in the current hydrocarbon accumulation.
Qinqi XU, Chenglin CHU, Xiaowen GUO, Yongli LIU, Li ZHANG, Mingxia LUO   +5 more
doaj   +1 more source

Identification of Ideal Allele Combinations for the Adaptation of Spring Barley to Northern Latitudes

Frontiers in Plant Science, 2019
The northwards expansion of barley production requires adaptation to longer days, lower temperatures and stronger winds during the growing season. We have screened 169 lines of the current barley breeding gene pool in the Nordic region with regards to ...
Magnus Göransson, Magnus Göransson, Jón Hallsteinn Hallsson, Morten Lillemo, Jihad Orabi, Gunter Backes, Ahmed Jahoor, Ahmed Jahoor, Jónatan Hermannsson, Therese Christerson, Stine Tuvesson, Bo Gertsson, Lars Reitan, Muath Alsheikh, Reino Aikasalo, Mika Isolahti, Merja Veteläinen, Marja Jalli, Lene Krusell, Rasmus L. Hjortshøj, Birger Eriksen, Therése Bengtsson   +21 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

GPC-YOLO: An Improved Lightweight YOLOv8n Network for the Detection of Tomato Maturity in Unstructured Natural Environments

Sensors
Effective fruit identification and maturity detection are important for harvesting and managing tomatoes. Current deep learning detection algorithms typically demand significant computational resources and memory.
Yaolin Dong, Jinwei Qiao, Na Liu, Yunze He, Shuzan Li, Xucai Hu, Chengyan Yu, Chengyu Zhang   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Teff (Eragrostis tef) dry matter yield, nutrient uptake partitioning, and nitrogen use efficiency indices affected by nitrogen rate under balanced fertilization

Sustainable Environment
Teff [Eragrostis tef (Zucc.) Trotter] has gained high demand and popularity across the world in recent years. Data on nutrient uptake and partitioning and nitrogen use efficiency (NUE) indices of teff under balanced fertilization are scarce. A greenhouse
Mulugeta Demiss, Upendra Singh, Job Fugice, Zachary P. Stewart, Latha Nagarajan   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Towards a Smart Evaluation Model for Assessing Transport Providers’ Maturity in Support of Logistic Sustainability

Engineering Proceedings
The development of the supply chain’s outsourcing and globalization has intensified the requirement for sustainable transport. The evaluation of the transport providers’ maturity, which is crucial to all and any achievements in this context, is hampered ...
Hicham El Abdellaoui, Adil Bellabdaoui
doaj   +1 more source