Results 121 to 130 of about 148,818 (311)

Smart Contract Maturity Model

open access: yes, 2023
A smart contract is a recently emerging technology which enables agreement to be automatable by computers and enforceable by legal enforcement or tamper-proof execution of code.
van Raalte, Jordy Jordanus Cornelius
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Assessing Risk Management Capability of Public Sector Organizations Related to PPP Scheme Development for Water Supply in Indonesia

open access: yesCivil Engineering Dimension, 2012
The success of Public Private Partnership (PPP) for water supply investment is inseparable from the capability of risk management of the parties within the project.
Pangeran M.H.   +3 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A framework for measuring & improving CX : white paper

open access: yes, 2017
A growing number of global organisations are using the Customer Experience Management (CEM) Maturity Model to benchmark their customer experience development and identify where improvements need to be made.
MacGillavry, Kim   +2 more
core  

Development of a social and environmental determinants of health informatics maturity model. [PDF]

open access: yesJ Clin Transl Sci, 2023
Espinoza JC   +6 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Cloud data governance maturity model

open access: yes
To ensure data governance in cloud computing, it is important to build-in data governance in the planning, strategy and the design phases of cloud computing and adapt a data governance program architecture which makes sure that regular and governance ...
Al-Ruithe, Majid Saliman   +1 more
core   +1 more source

Capability maturity model integration (CMMI) [PDF]

open access: yes, 2014
Capability Maturity Model Integration or CMMI (Capability Maturity Model Integration) is a combination of process improvement models for what is systems engineering, and software, is derived from CMM, differentiating itself from this by the integration ...
Morales Fernández, Rogelio   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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