Results 81 to 90 of about 154 (154)

PD‐L1, PD‐1, and CTLA‐4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment

Veterinary and Comparative Oncology, Volume 23, Issue 2, Page 141-151, June 2025.
ABSTRACT Canine oral melanoma (OM) exhibits poor prognosis and limited treatment options. The success of immune checkpoint inhibitors (ICIs) in human melanoma has driven interest in similar therapeutic approaches in the dog, although the immunosuppressive mechanisms adopted by canine OM remain unclear. This study aimed to evaluate the expression of the
Greta Foiani, Erica Melchiotti, Katia Capello, Ilaria Porcellato, Chiara Brachelente, Selina Iussich, Davide Giacobino, Emanuela Morello, Marina Martano, Paolo Buracco, Marta Vascellari   +10 more
wiley   +1 more source

First report of a papillomavirus‐induced viral plaque in the mouth of a dog

Veterinary Dermatology, EarlyView.
A mass that was histologically consistent with a pigmented viral plaque developed in the mouth of a dog. Canis familiaris papillomavirus type 16, which has been detected in cutaneous viral plaques, was amplified from the lesion. This is the first report of an oral viral plaque in a dog.
John S. Munday, Paul Hobson, Cynthia M. Bell   +2 more
wiley   +1 more source

Suspected Calvarial Hyperostosis Syndrome Causing Different Ophthalmological Signs in Two Young Labrador Retrievers—Case Report

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To describe calvarial hyperostosis syndrome (CHS) as a potential and unusual cause of exophthalmos or epiphora in young dogs. Animals Studied A nine‐month‐old female intact (case 1) and a two‐year‐old male intact Labrador Retriever (case 2). Procedures Patient history, including previous treatments, was documented.
Andrea Steinmetz, Stefan Kohl
wiley   +1 more source

Diagnosis and Treatment of Idiopathic Bone Cavity in the Mandible: A Case Report

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Idiopathic bone cavity of the mandible can often be identified in a radiographic exam. If detected, physicians should conduct follow‐up every 3–6 months, with surgical intervention considered only if the lesion becomes large or symptomatic.
Bryan Do Nguyen, Elham Radan
wiley   +1 more source

Surgical Approaches to Pre‐Auricular Cutaneous Squamous Cell Carcinomas Extending to the Temporal Bone

Head &Neck, Volume 47, Issue 6, Page 1736-1748, June 2025.
ABSTRACT Background Standardized surgical approaches to advanced pre‐auricular cutaneous squamous cell carcinomas (cSCC) are lacking. Methods Fifty–four patients who underwent lateral temporal bone resection (LTBR) for pre‐auricular cSCC were grouped into “Levels” of increasing disease spread.
Michael Schachtel, Mitesh Gandhi, James Bowman, Mark Midwinter, Benedict Panizza   +4 more
wiley   +1 more source

Phase II Trial of Hypofractionated Radiotherapy and Immunochemotherapy in Primary Refractory Diffuse Large B‐Cell Lymphoma: Preliminary Results and Insights from Digital Spatial Profiling

MedComm, Volume 6, Issue 6, June 2025.
This prospective study evaluates hypofractionated radiotherapy combined with zimberelimab in primary refractory DLBCL. A 61.5% complete response rate was achieved in the first stage. Digital spatial profiling analysis revealed T cell–lymphoma interactions and linked T cell infiltration to resistance.
Yong Yang, Jing Yu, Xiao‐Mei Hu, Si‐Lin Chen, Rui‐Zhi Zhao, Cheng Huang, Jiang‐Rui Guo, Tian‐Lan Tang, Cheng Chen, Yu‐Ping Lin, Ying Wang, Tian‐Xiu Liu, Hao Zheng, Si‐Qin Liao, Jin‐Hua Chen, Hai‐Ying Fu, Ting‐Bo Liu   +16 more
wiley   +1 more source

Intermediate Grade Salivary Gland Mucoepidermoid Carcinoma: Is Neck Dissection Indicated?

Otolaryngology–Head and Neck Surgery, Volume 172, Issue 6, Page 1988-1994, June 2025.
Abstract Objective NCCN guidelines recommend a neck dissection addressing at least levels II‐IV for high‐grade mucoepidermoid carcinoma (MEC) and close observation of the lymphatic basins for low‐grade MEC. However, no guidelines exist for intermediate‐grade MEC with clinically and radiologically uninvolved cervical lymph nodes.
Jake Langlie, Nicholas DiStefano, Carmen Gomez‐Fernandez, Jaylou Velez‐Torres, Jason Leibowitz, David Arnold, Donald Weed, Francisco J. Civantos   +7 more
wiley   +1 more source

Diagnosis and successful treatment of open pyometra in a wild European brown hare (Lepus europaeus)

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract This case report describes an open pyometra in a wild adult female hare (Lepus europaeus) that was rescued in the Umbria countryside (Italy) during mid‐January. The clinical signs observed included anorexia and a mucopurulent to haemorrhagic discharge from the vulva.
Claudia Massone, Oriana Cianca, Isabella Costantino, Daniele Marini, Domenico Caivano   +4 more
wiley   +1 more source

Fluoroscopic guidance for bulla identification during ventral bulla osteotomy in eight French bulldogs

Veterinary Record Open, Volume 12, Issue 1, June 2025.
Abstract Objective To describe the technique and outcome of fluoroscopy to guide bulla identification in French bulldogs during ventral bulla osteotomy. Materials and methods Medical records of eight French bulldogs with otitis media that underwent a fluoroscopic‐guided ventral bulla osteotomy between January 2020 and June 2023 were reviewed ...
Hui Yu Lu, Jeffery J. Biskup, Lea R. Mehrkens, Debbie Reynolds   +3 more
wiley   +1 more source

The Synergetic Effect of Periodontal Therapy and TNF‐α Inhibitor for the Treatment of Comorbid Periodontitis and Psoriasis

Journal of Clinical Periodontology, Volume 52, Issue 6, Page 907-919, June 2025.
ABSTRACT Aim To assess the adjunctive effect of periodontal therapy on psoriasis‐related outcomes in a combined experimental model of ligature‐induced periodontitis and Imiquimod (IMQ)‐induced psoriasis. Also, this experiment aimed to study the impact of TNF‐α inhibitors on the periodontium.
Crystal Marruganti, Carlo Gaeta, Chiara Falciani, Elisa Cinotti, Pietro Rubegni, Mario Alovisi, Nicola Scotti, Andrea Baldi, Cristiana Bellan, Chiara Defraia, Elena Bertaggia, Fabio Fiorino, Silvia Valensin, Erika Bellini, Antonella De Rosa, Filippo Graziani, Francesco D'Aiuto, Simone Grandini   +17 more
wiley   +1 more source