Results 31 to 40 of about 99,053 (255)

Using biomodels for maxillofacial surgeries: 10 years of experience in a Brazilian public service

Brazilian Journal of Oral Sciences, 2015
Aim: To evaluate 10 years of experience of use of biomodels at the Department of Oral and Maxillofacial Surgery of the Piracicaba Dental School, University of Campinas (UNICAMP), Brazil, showing the difficulties and importance of using biomodels in a ...
Gabriela Mayrink, Luciana Asprino, Roger William Fernandes Moreira, Gustavo Henrique de Lima Paschoal, Pedro Noritomi, Márcio de Moraes   +5 more
doaj   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

FREQUENCY OF HEPATITIS B AND C IN ORAL AND MAXILLOFACIAL SURGERY PATIENTS AT ARMED FORCES INSTITUTE OF DENTISTRY

Pakistan Armed Forces Medical Journal, 2018
Objective: To see the frequency of hepatitis B virus (HBV) and hepatitis C virus (HCV) carriers in oral and maxillofacial surgical patients. Study Design: Descriptive study.
Adnan Babar, Muhammad Waseem Ibrahim, Irfan Shah, Pareesa Rehman, Muhammad Usman Ali Awan, Muhammad Amin   +5 more
doaj   +2 more sources

Retrospective Analysis of Surgically Managed Maxillofacial Fractures in Kayseri Training and Research Hospital

Turkish Archives of Otorhinolaryngology, 2016
Objective: To retrospectively evaluate the clinical and surgical data of patients with maxillofacial fracture (MFF) who were surgically treated at the Department of ENT and Head Neck Surgery in the Kayseri Training and Research Hospital and to compare ...
Mehmet Yaşar, Ali Bayram, Murat Doğan, Mustafa Sağit, Altan Kaya, İbrahim Özcan, Cemil Mutlu   +6 more
doaj   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Assessment of Occupational Stress Among Oral and Maxillofacial Surgeons and Residents in Saudi Arabia: A Cross-Sectional Study

Advances in Medical Education and Practice, 2020
Mohammed Alkindi,1 Osama Alghamdi,1 Hourya Alnofaie,2,3 Ziyad AlHammad,4 Mohammed Badwelan,1 Sahar Albarakati5 1Oral and Maxillofacial Surgery Department, College of Dentistry, King Saud University, Riyadh, Saudi Arabia; 2Oral and Maxillofacial Surgery ...
Alkindi M, Alghamdi O, Alnofaie H, AlHammad Z, Badwelan M, Albarakati S   +5 more
doaj  

Immunomodulation for maxillofacial reconstructive surgery

Maxillofacial Plastic and Reconstructive Surgery, 2020
Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the ...
Seong-Gon Kim
doaj   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source