Results 221 to 230 of about 134,540 (296)

An improved Wexler algorithm for electrical impedance tomography using finite element method and gradient based overrelaxation. [PDF]

Sci Rep
Jurgielewicz M, Walczyk CJ.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Finite element analysis of the modified intramedullary nail-II for managing reverse obliquity trochanteric fractures. [PDF]

Sci Rep
Wang Q, Lu Y, Liu L, Ma T, Li Z, Zhang K, Huang Q.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Spinal Compression Fracture Mechanisms in Mountain Biking: An Accident Reconstruction Approach. [PDF]

Global Spine J
Bonte S, Olgiati G, Thouzé A, Arnoux PJ, Thollon L, Bailly N.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A general mechanism of airborne hearing in recent and early non-tympanate tetrapods. [PDF]

J Exp Biol
Christensen-Dalsgaard J, Lauridsen TB, Capshaw G, Carr CE.   +3 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

In Vitro Experimental Study of Biofiligree^® Osteosynthesis in Calcaneus Fracture Fixation. [PDF]

Bioengineering (Basel)
Ramos A, Noronha O, Simões O, Noronha J, Simões J.   +4 more
europepmc   +1 more source