Results 181 to 190 of about 11,564,321 (250)

Pre‐operative three‐dimensional face scans for predicting difficult facemask ventilation: a prospective development study

open access: yesAnaesthesia, Volume 81, Issue 10, Page 1340-1348, October 2026.
Summary Introduction Facemask ventilation is a key airway management skill but predicting difficulty can be challenging. Pre‐operative three‐dimensional face scanning may have diagnostic value. We aimed to identify interpretable facial shape features and to quantify their value for predicting difficult facemask ventilation.
Viktor A. Wünsch   +9 more
wiley   +1 more source

Concavity of the maximal expiratory flow-volume curve, and incidence of COPD and respiratory symptoms: a population-based cohort study. [PDF]

open access: yesERJ Open Res
Tan DJ   +11 more
europepmc   +1 more source

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6132-6153, October 2026.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon   +3 more
wiley   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3202-3213, September 2026.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas   +16 more
wiley   +1 more source

Dynamic hyperinflation occurs in healthy subjects during maximal voluntary ventilation. [PDF]

open access: yesFront Med (Lausanne)
Herpeux A   +5 more
europepmc   +1 more source

CCR2/CCR5 Signaling Defines a Pathogenic Interstitial Macrophage Subset That Drives Severe Asthma

open access: yesClinical and Translational Allergy, Volume 16, Issue 9, September 2026.
In mouse model of severe asthma, protective resident alveolar macrophages are depleted and replaced by monocyte‐derived populations, particularly a Lyve1loMHCIIhi interstitial macrophage subset enriched for Ccr2/Ccr5 and inflammatory gene programs. Blocking this subset with a dual CCR2/CCR5 antagonist reduces airway inflammation, restores homeostasis ...
Hao Wang   +8 more
wiley   +1 more source

Development and validation of a multimodal risk prediction model for early COPD progression: a retrospective study integrating clinical, functional, and CT radiomic features. [PDF]

open access: yesTher Adv Respir Dis
Zhang J   +13 more
europepmc   +1 more source

Patient‐Specific Computational Fluid Dynamics Modeling of Airway Collapse in Infants With Robin Sequence

open access: yesInternational Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 9, September 2026.
This study presents a novel method to analyze the airflow dynamics across the full respiratory cycle in Robin Sequence infants with upper airway obstruction or collapse. It uses 4DCT‐derived airway anatomy and wall movement combined with Computational Fluid Dynamics simulations.
Gautam Jalori   +5 more
wiley   +1 more source

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