Results 261 to 270 of about 693,697 (314)

Acute Impact of Transcatheter Edge-to-Edge Repair of Tricuspid Regurgitation on Right Ventricular Hemodynamics. [PDF]

open access: yesJ Am Heart Assoc
Reil JC   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Puberty-Associated Emergence of Hypertrophic Cardiomyopathy: When Genetics Meets Growth. [PDF]

open access: yesJACC Case Rep
Mashiah G   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Discrete stochastic maximal regularity. [PDF]

open access: yesMath Ann
Evangelopoulos-Ntemiris F, Veraar M.
europepmc   +1 more source

Microbial metabolite Enterobactin impairs mitochondrial respiration and alleviates colitis. [PDF]

open access: yesGut Microbes
Kushwaha V   +6 more
europepmc   +1 more source

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