Results 41 to 50 of about 5,021,065 (259)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The convolution algebra H1(R)

open access: yesJournal of Function Spaces and Applications, 2010
H1(R) is a Banach algebra which has better mapping properties under singular integrals than L1(R) . We show that its approximate identity sequences are unbounded by constructing one unbounded approximate identity sequence {vn}.
R. L. Johnson, C. R. Warner
doaj   +1 more source

Activating hidden teleportation power: Theory and experiment

open access: yesPhysical Review Research, 2021
Ideal quantum teleportation transfers an unknown quantum state intact from one party Alice to the other Bob via the use of a maximally entangled state and the communication of classical information. If Alice and Bob do not share entanglement, the maximal
Jyun-Yi Li   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The maximal ideal space of the functions locally in a function algebra. [PDF]

open access: yesProceedings of the American Mathematical Society, 1963
1. R. Arens and K. Hoffman, Algebraic extensions of normed algebras, Proc. Amer. Math. Soc. 7 (1956), 203-210. 2. J. A. Lindberg, Jr., Algebraic extensions of commutative Banach algebras, (to appear). 3. , Polynomials over Banach algebras, (to appear). 4. L. H. Loomis, An introduction to abstract harmonic analysis, Van Nostrand, New York, 1953. 5. C. E.
openaire   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Simultaneous working fluid and expander selection method for reaching low‐threshold technology organic Rankine cycle (ORC) design

open access: yesEnergy Science & Engineering, 2023
Maximizing the utilization of an available source serves as the ideal approach, provided that only technical factors are considered. For sources with low heat flux, however, cost‐effective solutions are more suitable due to the minimal net power ...
Axel Groniewsky   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Q* Index: A Useful Global Measure of Dementia Screening Test Accuracy

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2015
Background/Aims: Single, global or unitary, indicators of test diagnostic performance have intuitive appeal for clinicians. The Q* index, the point in receiver operating characteristic (ROC) curve space closest to the ideal top left-hand corner and where
A.J. Larner
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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