Results 91 to 100 of about 2,710,426 (336)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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Complete Closedness of Maximal Monotone Operators [PDF]
(This paper is dedicated to the memory of Professor Kwan Chao-Chin, former academic member and director of the Institute of System Science of the Academy of Chinese Sciences.) A maximal monotone operator in Rn is completely closed, i.e., not only closed for points, but also closed for directions. Such a completely closed operator is locally bounded at
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
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Maximal operator in Dunkl-Fofana spaces
POKOU NAGACY, JUSTIN FEUTO
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In this paper, the almost everywhere convergence of Cesàro means of Walsh–Kaczmarz–Fourier series in a varying parameter setting is investigated. In particular, we define subsequence ℕαn,q{{\mathbb{N}}_{{{\alpha }_{n}},q}} of natural numbers and prove ...
Adimasu Anteneh Tilahun
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
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The Maximal Regularity of Nonlinear Second-Order Hyperbolic Boundary Differential Equations
In this paper, we show the maximal regularity of nonlinear second-order hyperbolic boundary differential equations. We aim to show if the given second-order partial differential operator satisfies the specific ellipticity condition; additionally, if ...
Xingyu Liu
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
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On the Non-Compactness of Maximal Operators
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source

