Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Inverse association between triglyceride-glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study. [PDF]
Zhang B +7 more
europepmc +1 more source
A Geometrically Transient Platform for Bioelectronic Implants
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik +13 more
wiley +1 more source
The higher the fraction of maximal oxygen uptake is during interval training, the greater is the cycling performance gain. [PDF]
Odden I +7 more
europepmc +1 more source
Field‐programmed anisotropy imparts material‐level intelligence to soft composites. Magnetic torque dynamics drive magneto‐piezoelectric nanowires from random dispersion into deterministic axial alignment. The resulting hierarchical percolation networks confine electromechanical coupling to specific axes and intrinsically decouple superposed force ...
Yubin Kim +9 more
wiley +1 more source
Factors affecting maximal oxygen uptake in prepubertal children: a systematic review and meta-analysis. [PDF]
Jurov I, Demšar J.
europepmc +1 more source
Stabilized Bi(III) Sites Direct *NH2OH Pathway for Efficient Cyclohexanone Oxime Electrosynthesis
The electron‐buffering effect stabilizes Bi3+ sites under electroreductive conditions, preserving a favorable interfacial water configuration that sustains the selective *NH2OH pathway and enables efficient cyclohexanone oxime electrosynthesis. ABSTRACT Coupling electrocatalytic nitrite reduction reaction (NO2−RR) with cyclohexanone conversion enables ...
Zichao Xi +8 more
wiley +1 more source
Correction: Variations of training load, monotony, and strain and dose-response relationships with maximal aerobic speed, maximal oxygen uptake, and isokinetic strength in professional soccer players. [PDF]
Clemente FM +6 more
europepmc +1 more source
A reusable contact‐type pre‐lithiation platform enables uniform, precisely controllable pre‐lithiation at low stack pressure, suppressing interfacial degradation and thereby markedly improving initial Coulombic efficiency and cycling performance in all‐solid‐state batteries.
Yunho Lee +10 more
wiley +1 more source
The Effect of Polarized Training Intensity Distribution on Maximal Oxygen Uptake and Work Economy Among Endurance Athletes: A Systematic Review. [PDF]
Nøst HL, Aune MA, van den Tillaar R.
europepmc +1 more source

