Results 81 to 90 of about 328,728 (289)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Simple form of a projection set in hybrid iterative schemes for non-linear mappings, application of inequalities and computational experiments

Journal of Inequalities and Applications, 2018
Some relaxed hybrid iterative schemes for approximating a common element of the sets of zeros of infinite maximal monotone operators and the sets of fixed points of infinite weakly relatively non-expansive mappings in a real Banach space are presented ...
Li Wei, Ravi P. Agarwal
doaj   +1 more source

A Strong Convergence Theorem for a Finite Family of Bregman Demimetric Mappings in a Banach Space under a New Shrinking Projection Method

Journal of Function Spaces, 2021
In this paper, using a new shrinking projection method and new generalized k-demimetric mappings, we consider the strong convergence for finding a common point of the sets of zero points of maximal monotone mappings, common fixed points of a finite ...
Bijan Orouji, Ebrahim Soori, Donal O’Regan, Ravi P. Agarwal   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Convergence Theorems for Maximal Monotone Operators, Weak Relatively Nonexpansive Mappings and Equilibrium Problems

Journal of Applied Mathematics, 2012
We introduce hybrid-iterative schemes for solving a system of the zero-finding problems of maximal monotone operators, the equilibrium problem, and the fixed point problem of weak relatively nonexpansive mappings. We then prove, in a uniformly smooth and
Kamonrat Nammanee, Suthep Suantai, Prasit Cholamjiak   +2 more
doaj   +1 more source

On the Volume of Sections of the Cube

Analysis and Geometry in Metric Spaces, 2021
We study the properties of the maximal volume k-dimensional sections of the n-dimensional cube [−1, 1]n. We obtain a first order necessary condition for a k-dimensional subspace to be a local maximizer of the volume of such sections, which we formulate ...
Ivanov Grigory, Tsiutsiurupa Igor
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Effects of long term supplementation of anabolic androgen steroids on human skeletal muscle. [PDF]

PLoS ONE, 2014
The effects of long-term (over several years) anabolic androgen steroids (AAS) administration on human skeletal muscle are still unclear. In this study, seventeen strength training athletes were recruited and individually interviewed regarding self ...
Ji-Guo Yu, Patrik Bonnerud, Anders Eriksson, Per S Stål, Yelverton Tegner, Christer Malm   +5 more
doaj   +1 more source

Affine semigroups of maximal projective dimension-II

Semigroup Forum
If the Krull dimension of the semigroup ring is greater than one, then affine semigroups of maximal projective dimension ($\mathrm{MPD}$) are not Cohen-Macaulay, but they may be Buchsbaum. We give a necessary and sufficient condition for simplicial $\mathrm{MPD}$-semigroups to be Buchsbaum in terms of pseudo-Frobenius elements.
Bhardwaj, Om Prakash, Sengupta, Indranath   +1 more
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source