Results 231 to 240 of about 988,365 (280)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

From Common Information to Canonical Correlation Analysis and Beyond: Bridging Information Theory, Signal Processing, and Machine Learning. [PDF]

Entropy (Basel)
Karakasis PA, Saad W.
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Anthropometric Profile, Body Composition, and Game Performance of the Mexican Professional Basketball League Champion Team During the 2025-2026 Basketball Champions League Americas: A Cross-Sectional Study. [PDF]

J Funct Morphol Kinesiol
Herrera-Amante CA, Villaseca-Vicuña R, Yáñez-Sepúlveda R, Jaime-González BC, Hoyos-Flores JR, Garcia-Carrillo E, Morán-Bravo M, Becerra-Patiño BA, López-Gil JF.   +8 more
europepmc   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Physiological Factors of Exercise Intolerance in Patients With Pectus Excavatum: A Retrospective, Single-Center Study. [PDF]

Cureus
Chen R, Zhang R, Kakavand B.
europepmc   +1 more source

A systematic and critical review of measurement scales for evaluating gastrointestinal symptoms during exercise. [PDF]

J Int Soc Sports Nutr
Aitkenhead R, Waldron M, Conway GE, Horner K, Heffernan SM.   +4 more
europepmc   +1 more source

Laminar organization of cellular microcircuits modulating human interictal epileptiform discharges. [PDF]

Nat Neurosci
Silva AB, Marathe SA, Greicius QR, Xu D, Jain S, Chung JE, Yang X, Khambhati AN, Leonard MK, Kleen JK, Chang EF.   +10 more
europepmc   +1 more source