Results 111 to 120 of about 101,397 (323)

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

open access: yesAdvanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer   +8 more
wiley   +1 more source

Maximal $L_{p} $-regularity for a second-order differential equation with unbounded intermediate coefficient

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
We consider the following equation \[-y''+r\left(x\right)y'+q\left(x\right)y=f(x), \] where the intermediate coefficient $r$ is not controlled by $q$ and it is can be strong oscillate. We give the conditions of well-posedness in $L_{p} \left(-\infty ,\,
Kordan Ospanov
doaj   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

open access: yesAdvanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Solution formula for generalized two-phase Stokes equations and its applications to maximal regularity: Model problems

open access: yesAIMS Mathematics
In this paper, we give a solution formula for the two-phase Stokes equations with and without surface tension and gravity over the whole space with a flat interface. The solution formula has already been considered by Shibata and Shimizu.
Naoto Kajiwara
doaj   +1 more source

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani   +4 more
wiley   +1 more source

Maximal Lp -Lq regularity to the Stokes problem with Navier boundary conditions

open access: yesAdvances in Nonlinear Analysis, 2017
We prove in this paper some results on the complex and fractional powers of the Stokes operator with slip frictionless boundary conditions involving the stress tensor.
Al Baba Hind
doaj   +1 more source

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

open access: yesAdvanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat   +6 more
wiley   +1 more source

Subgrain and Cavity Development during Creep of Al‐3.85%Mg

open access: yesAdvanced Engineering Materials, EarlyView.
Al‐3.85%Mg does form subgrains if crept at very high strains. This fact allows the unification of the creep description in two different alloys such as pure Al and Al–Mg alloys. It is classically considered that the creep mechanisms for type M (e.g., pure Al) and type A alloys (e.g., Al–Mg alloys) are different.
Augusta Isaac   +6 more
wiley   +1 more source

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