Results 221 to 230 of about 686,790 (292)
ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang +5 more
wiley +1 more source
Acute and Chronic Effects of Accentuated Eccentric Loading vs. Constant-Load Resistance Training: A Systematic Review and Meta-analysis. [PDF]
Zhang X +4 more
europepmc +1 more source
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu +10 more
wiley +1 more source
Does acute caffeine ingestion improve high-intensity interval exercise performance? A systematic review and meta-analysis. [PDF]
Peng Y +5 more
europepmc +1 more source
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng +7 more
wiley +1 more source
Transcranial magnetic stimulation-based evaluation of exercise training-induced changes in TMS-derived neurophysiological markers and motor performance in healthy adults: a systematic review and meta-analysis of RCTs. [PDF]
Gao Y, Zhen Z, Hu J.
europepmc +1 more source
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang +15 more
wiley +1 more source

