Results 291 to 300 of about 1,367,812 (370)

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

Advanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang, Shucheng Jin, Penghui Guo, Yuying Yin, Yichun Hua, Xiaosheng Ding, Zhe Zhang, Shuo Chen, Xu Han, Baowang Li, Yan Liu, Xiaoyan Li, Deling Li, Jing Jing, Wei Shi, Wang Jia   +15 more
wiley   +1 more source

Pulmonary Rehabilitation Reduces Airway Inflammation in Asthma Patients with High Fe_NO Levels. [PDF]

J Asthma Allergy
Gloeckl R, Kroll D, Abdulleyev G, Schneeberger T, Jarosch I, Nell C, Koczulla AR.   +6 more
europepmc   +1 more source

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

Advanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao, Yaqin Huang, Jiazhong Shi, Xiaozhou Zhou, Johan Bourghardt Fagman, Liwei Wang, Sha Liu, Wuxing Wang, Yuting Liu, Zhiwen Chen, Jin Yang   +10 more
wiley   +1 more source

Effects of blood flow restriction training on aerobic capacity and performance in endurance athletes: a systematic review and meta-analysis. [PDF]

BMC Sports Sci Med Rehabil
Zhang Z, Gao X, Gao L.
europepmc   +1 more source

Atomic‐Level Structural Characteristics of β‐Relaxation in Metallic Glasses

Advanced Science, EarlyView.
Using in situ synchrotron radiation X‐ray techniques, this study experimentally characterizes β‐relaxation at the atomic scale, linking it explicitly to tricapped trigonal prism (TTP)‐like atomic structures and fast atomic motions. Cyclic heating reveals β‐relaxation as irreversible yet reactivatable through rejuvenation, offering unprecedented insight
Tianding Xu, Jinquan Zhou, Xiao‐Dong Wang, Ke Yang, Qing‐Ping Cao, Dong‐Xian Zhang, Chih‐Wen Pao, Jian‐Zhong Jiang   +7 more
wiley   +1 more source

Impact of Prehabilitation Components on Oxygen Uptake of People Undergoing Major Abdominal and Cardiothoracic Surgery: A Network Meta-Analysis of Randomized Controlled Trials. [PDF]

J Clin Med
Priego-Jiménez S, Priego-Jiménez P, López-González M, Martinez-Rodrigo A, López-Requena A, Álvarez-Bueno C.   +5 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

The effect of sprint interval training on key cardiometabolic risk factors in children and adolescents: a systematic review and meta-analysis. [PDF]

Front Physiol
Liang W, Dai J, Liu C, Yan X, Xu S, Huang W.   +5 more
europepmc   +1 more source

Feasibility and Safety of an Outdoor-Simulated Interactive Indoor Cycling Device for Cardiac Rehabilitation: A Pilot Validation Study. [PDF]

J Clin Med
Lee JT, Kim BR, Pyun SB, Kim YM, Son HS, Jung JS, Kim HJ.   +6 more
europepmc   +1 more source