A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu +18 more
wiley +1 more source
Association of the triglyceride-glucose index and its derived indices with carotid artery plaques in postmenopausal women: a cross-sectional study. [PDF]
Chen X +5 more
europepmc +1 more source
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Safety and efficacy of switching from dulaglutide to tirzepatide across clinically relevant baseline characteristics in participants with T2D: subgroup analysis of SURPASS-SWITCH. [PDF]
Violante-Ortiz R +5 more
europepmc +1 more source
A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun +12 more
wiley +1 more source
Construction and validation of a palmitoylation-related prognostic model for lung adenocarcinoma based on integrated bioinformatics and machine learning. [PDF]
Huang Z +7 more
europepmc +1 more source
This work clarifies why organic semiconductors perform differently in photovoltaic devices and photocatalytic nanoparticles. By examining D18:Y5 and PM6:Y6 systems, we show how aggregation, exciton lifetime, and interfacial charge transfer behavior govern energy‐conversion pathways.
Gayoung Ham +14 more
wiley +1 more source
Efficacy and safety of orforglipron, an oral small-molecule GLP-1 receptor agonist, on cardiometabolic outcomes: a meta-analysis and systematic review. [PDF]
Alper A +6 more
europepmc +1 more source
Non-existence of abelian maximal subgroups in cyclic division algebras
Huynh Viet Khanh
openalex +1 more source

