Results 81 to 90 of about 172,503 (322)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Maximal Subgroups of Compact Lie Groups

open access: yes, 2013
This report aims at giving a general overview on the classification of the maximal subgroups of compact Lie groups (not necessarily connected). In the first part, it is shown that these fall naturally into three types: (1) those of trivial type, which ...
Antoneli, Fernando   +2 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Some designs and codes from L_2(q) [PDF]

open access: yesTransactions on Combinatorics, 2014
For $q \in \{7,8,9,11,13,16\}$, we consider the primitive actions of $L_2(q)$ and use Key-Moori Method 1 as described in [Codes, designs and graphs from the Janko groups {$J_1$} and {$J_2$}, {\em J. Combin. Math. Combin.
Jamshid Moori   +1 more
doaj  

Some results on compact convergence semigroups defined by filters

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1998
In this paper the concept of convergence defined by filters is used and applied in the study of semigroups. Special emphasis is placed on compact convergence semigroups and their properties.
Phoebe Ho, Paul Plummer, Shing So
doaj   +1 more source

On θ-pairs for maximal subgroups

open access: yesJournal of Pure and Applied Algebra, 2000
A pair of subgroups \((C,D)\) of a finite group \(G\) is said to be a \(\theta^*\)-pair for a maximal subgroup \(M\) of \(G\) if it satisfies the following properties: (a) \(D\) is a proper subgroup of \(C\) and \(D\) is normal in \(G\). (b) \(D\) is contained in \(M\) and \(M\) does not contain any conjugate of \(C\) in \(G\).
Shirong, Li, Yaoqing, Zhao
openaire   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Independence and maximal subgroups

open access: yesIllinois Journal of Mathematics, 1996
\(G\) denotes a finite group and \(M(G)\) the set of all maximal subgroups of \(G\). A simplicial complex \((M,{\mathcal T})\) is a finite set \(M\) and a set \(\mathcal T\) of subsets of \(M\) such that: (1) If \(m\in M\), then \(\{m\}\in{\mathcal T}\). (2) If \(A\in{\mathcal T}\) and \(B\subset A\), then \(B\in{\mathcal T}\).
openaire   +3 more sources

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