Results 131 to 140 of about 385,717 (303)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Morning–evening differences of short-term maximal performance and psychological variables in female athletes

Frontiers in Physiology
The aim of this study was to examine the effect of time of day on short-term maximal performance and psychological variables in young females. Fifteen active women participated in the study (age: 22 ± 3 years) and completed Hooper and the POMS-F ...
Wafa Jribi, Wafa Jribi, Houda Bougrine, Houda Bougrine, Ali Aloui, Ali Aloui, Jihen Khalfoun, Nafaa Souissi, Nafaa Souissi, Wajdi Mkacher, Wajdi Mkacher, Kais El Abed, Kais El Abed, Abderraouf Ben Abderrahman, Abderraouf Ben Abderrahman   +14 more
doaj   +1 more source

ENUMERATIONS OF MAXIMAL CHAINS AND FLAGS OVER FUZZY GROUP STRUCTURES

, 2018
In this paper, we introduce the new term synonymous to a series, namely a flag. We amongst other things, fix some terminology includes flags, maximal chains, pinned flags and various other terms with respect to finite abelian groups.
S. Sivakumar, N. Rajakumari
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Central and peripheral determinants of fatigue in acute hypoxia

, 2011
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University on 24th March 2011.Fatigue is defined as an exercise-induced decrease in maximal voluntary force produced by a muscle. Fatigue may arise from central and/or
Goodall, Stuart
core  

Long term bed rest with and without vibration exercise countermeasures: Effects on human muscle protein dysregulation

, 2010
The present investigation, the first in the field, was aimed at analyzing differentially, on individual samples, the effects of 55 days of horizontal bed rest, a model for microgravity, on myosin heavy and myosin light chain isoforms distribution (by ...
Blottner, Dieter, Michele Vasso, Bonifacio, Gaetano, Cerretelli, Paolo, C. Fania, Vasso, Michele, Salanova, Michele, Jörn Rittweger, Moriggi, Manuela, Gaetano Bonifacio, D. Capitanio, M. Salanova, M. Vasso, D. Felsenberg, G. Bonifacio, Gelfi, Cecilia, C. Gelfi, D. Blottner, Rittweger, Jörn, Paolo Cerretelli, Dieter Blottner, Chiara Fania, Capitanio, Daniele, P. Cerretelli, Cecilia Gelfi, Daniele Capitanio, Felsenberg, Dieter, Michele Salanova, Dieter Felsenberg, Fania, Chiara, M. Moriggi, J. Rittweger, Manuela Moriggi   +32 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Asset Pricing Under The Quadratic Class [PDF]

We identify and characterize a class of term structure models where bond yields are quadratic functions of the state vector. We label this class the quadratic class and aim to lay a solid theoretical foundation for its future empirical application.
Markus Leippold, Liuren Wu
core  

Teste máximo de 3 minutos em ciclo-ergômetro isocinético: análise de reprodutibilidade e respostas fisiológicas em duas cadências de pedalada [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2012A partir da relação entre cargas de trabalho e os seus respectivos tempos de exaustão pode-se estabelecer ...
Lucas, Ricardo Dantas de
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Anticipatory pacing strategies during supramaximal exercise lasting longer than 30 s

, 2004
Purpose: This study assessed whether pacing strategies are adopted during supramaximal exercise bouts lasting longer than 30 s. Methods: Eight healthy males performed six Wingate anaerobic tests (WAnT).
Alan St, St Clair Gibson, Alan, Paula J. Robson, Ansley, Les, Robson, Paula J., Noakes, Timothy, Noakes, Timothy David, Noakes, Timothy D., Robson-Ansley, Paula, Les Ansley, Timothy D. Noakes, Clair Gibson   +11 more
core   +1 more source