Results 121 to 130 of about 607,371 (320)

Multipass Streaming Algorithms for Regularized Submodular Maximization [PDF]

open access: diamond, 2023
Qingin Gong   +3 more
openalex   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

A quantile variant of the expectation–maximization algorithm and its application to parameter estimation with interval data

open access: yesJournal of Algorithms & Computational Technology, 2018
The expectation–maximization algorithm is a powerful computational technique for finding the maximum likelihood estimates for parametric models when the data are not fully observed.
Chanseok Park
doaj   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma   +5 more
wiley   +1 more source

Unifying Optimization Algorithms to Aid Software System Users: optimx for R

open access: yesJournal of Statistical Software, 2011
R users can often solve optimization tasks easily using the tools in the optim function in the stats package provided by default on R installations. However, there are many other optimization and nonlinear modelling tools in R or in easily installed add ...
John C. Nash, Ravi Varadhan
doaj  

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

An effective branch and bound method to find the optimal solution of an assignment problem with maximization objective function

open access: yesMathematics Open
In this study, a different simple and successful branch and bound technique is constructed to find the best solution for the assignment problems with a maximization objective function without converting the objective function to minimization, as proposed
Jairos Kahuru Shinzeh, Halidi Ally Lyeme
doaj   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

GENERATION OF COMPLEX NONLINEAR BENCHMARK FUNCTIONS FOR OPTIMIZATION USING FUZZY SETS AND CLASSICAL TEST FUNCTIONS GENERACIÓN DE FUNCIONES BENCHMARK COMPLEJAS NO LINEALES PARA OPTIMIZACIÓN USANDO CONJUNTOS DIFUSOS Y FUNCIONES DE PRUEBA CLÁSICAS

open access: yesRevista Ingenierías Universidad de Medellín, 2011
In this paper, we present a novel methodology to generate complex functions using two-dimensional fuzzy sets as weights for combining classical benchmark functions.
Eddy Mesa   +2 more
doaj  

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