Results 51 to 60 of about 607,371 (320)

Differentially Private Decomposable Submodular Maximization

open access: yes, 2020
We study the problem of differentially private constrained maximization of decomposable submodular functions. A submodular function is decomposable if it takes the form of a sum of submodular functions.
Chaturvedi, Anamay   +2 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Vulnerable maximizers: The role of decision difficulty [PDF]

open access: yesJudgment and Decision Making, 2017
Adding to prior literature that has examined the relationship between maximization and dissatisfaction, the present research suggests that maximizers, as defined by the original maximization scale, are unhappier decision makers than satisficers because ...
Kaeun Kim, Elizabeth G. Miller
doaj   +2 more sources

Randomized Composable Core-sets for Distributed Submodular Maximization

open access: yes, 2015
An effective technique for solving optimization problems over massive data sets is to partition the data into smaller pieces, solve the problem on each piece and compute a representative solution from it, and finally obtain a solution inside the union of
Balcan M.-F.   +4 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Maximally stiffening composites require maximally coupled rather than maximally entangled polymer species [PDF]

open access: yesSoft Matter, 2019
We couple Molecular Dynamics simulations with optical tweezers microrheology to discover that DNA–actin composites display maximal stiffening when the two species have similar number of entanglements and not when entanglements are maximized.
Davide Michieletto   +2 more
openaire   +4 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Optimizing Fundamental Frequencies in Axially Compressed Rotating Laminated Cylindrical Shells

open access: yesApplied Sciences
Optimizing composite materials, particularly in rotating structures, offers several practical benefits in the mechanical engineering and aerospace engineering industries.
Hsuan-Teh Hu, Yi-Wei Huang
doaj   +1 more source

Influence Maximization with Bandits [PDF]

open access: yes, 2016
We consider the problem of \emph{influence maximization}, the problem of maximizing the number of people that become aware of a product by finding the `best' set of `seed' users to expose the product to. Most prior work on this topic assumes that we know
Lakshmanan, Laks. V. S.   +2 more
core  

Conditioning moments of singular measures for entropy maximization II: Numerical examples

open access: yes, 2015
If moments of singular measures are passed as inputs to the entropy maximization procedure, the optimization algorithm might not terminate. The framework developed in our previous paper demonstrated how input moments of measures, on a broad range of ...
Budišić, Marko, Putinar, Mihai
core   +1 more source

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