Results 121 to 130 of about 829,480 (295)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
MathematicsAs people’s environment awareness increases and the “double carbon” policy is implemented, the new energy vehicle (NEV) becomes a popular form of transformation and more and more car manufacturers start to produce NEVs. Thus, how to choose an appropriate
Yunfei Zhang, Gaili Xu
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
水下无人系统学报In view of the effectiveness evaluation problems caused by the high complexity of the underwater equipment system, the strong stage characteristics of tasks, and the dynamically changing battlefield environment, this paper proposed a hierarchical ...
Zhenhua ZHANG +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Industrial Compressor Anti-Surge Computer Control
, 2007 The paper presents a compressor anti-surge control system, that results in maximizing compressor throughput with pressure standard deviation reduction, increased safety margin between design point and surge limit line and avoiding possible machine surge.
Ventzas Dimitrios, Petropoulos George
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Probabilities of maximal deviations for nonparametric regression function estimates
Journal of Multivariate Analysis, 1982 Let (X, Y) have regression function m(x) = E(Y X = x), and let X have a marginal density f1(x). We consider two nonparameteric estimates of m(x): the Watson estimate when f1 is known and the Yang estimate when f1 is known or unknown. For both estimates the asymptotic distribution of the maximal deviation from m(x) is proved, thus extending results of ...
openaire +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Maximizing the Benefits of Transitway Investment
, 2012 In the Twin Cities metropolitan area, significant long-range transit planning activities have been ongoing since the late 1990s. By 2030, the region is expected to have a network of fourteen transitways converging on the Minneapolis and St. Paul downtown
Fan, Yingling, Tilahun, Nebiyou Y.
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