Results 201 to 210 of about 829,480 (295)

Massive envenomations by bees in French Guiana: A ten-year retrospective study (2014-2023). [PDF]

PLoS Negl Trop Dis
Blaud R, Mutricy R, Negrello F, Eeckhout M, Epelboin L, Douine M, Kallel H, Fremery A.   +7 more
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

How reliable are ROC cut-offs? Evidence from simulation and empirical analysis. [PDF]

BMC Med Res Methodol
K Y, K P.
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Comparing the Antimicrobial Resistance Crisis to the COVID-19 Pandemic: A Randomized Public Health Messaging Experiment. [PDF]

Clin Infect Dis
Thorpe A, Lee RA, Szymczak JE, Farrell MC, Palmer I, Petty WB, Henderson T, Fagerlin A, Vaughn VM.   +8 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Comparative performance of machine learning and deep learning models for heart disease prediction in a small clinical dataset. [PDF]

Am J Cardiovasc Dis
Barootchi E, Zamani P, Birgani R, Bakhshi A, Zibaei P, Tafazolimoghadam A, Moeinipour Y, Doosti M, Deravi N, Khakpour Y, Farrokhi Z, Fathi M, Yarahmadi D.   +12 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Welfare-maximizing and profit-maximizing agroindustry location: A comparison

Traditionally, the location model has assumed that firms choose their location and input usage so as to maximize their profits. However, in the planning version of the location model, the industrial location might be selected on the basis of a welfare ...
Lin-Ti Tan
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