During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
ASME-Based Structural Assessment of Head-Shell Junctions in Pressurized Railway Tank Wagons. [PDF]
Ilincă CN +8 more
europepmc +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Assessing a low-dose copper treatment for dreissenid mussels: Effects on zebra mussel (Dreissena polymorpha) population. [PDF]
Barbour MT +8 more
europepmc +1 more source
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Assessment of heavy metals concentration in the sewage treatment pond of the Ahmadu Bello University
Heavy metal concentration of the water in the sewage treatment pond of the Ahmadu Bello University Zaria, Nigeria, was studied between April and September, 2007 using Energy Dispensive X-Ray Fluorescence (ED-XRF)analysis.
Tanimu, Y. +3 more
core
Evaluation of cytokine analytical performance and optimization of quality control strategies using the six sigma model: a multicenter study. [PDF]
Liu Q +5 more
europepmc +1 more source
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Numerical analysis of diaphragm wall behavior in a jet-grouted deep excavation: a random field case study. [PDF]
Nguyen HH, Le TN.
europepmc +1 more source

