Results 191 to 200 of about 745,346 (269)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Enhancing the Mechanical Performance of Laser Powder Bed Fusion Prepared 316L Stainless Steel by Deformation Post-Processing at Ambient Temperature. [PDF]

Materials (Basel)
Kocich R, Kunčická L.
europepmc   +1 more source

Influence of the training set on the generalizability of a model. For each dataset, models were trained on 100 different training sets containing 4 images each and were validated on the remaining images. The difference between the maximum and minimum Dice scores obtained for each sample across all runs was calculated and averaged over all samples. The standard deviation of the differences is also shown to provide a reference regarding the degree of variation observed among samples.

Matheus Viana da Silva (21433572), Natália de Carvalho Santos (21433575), Julie Ouellette (17041536), Baptiste Lacoste (10536857), Cesar H. Comin (3724186)   +4 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Pore structure and fractal characteristics of deep shale gas reservoirs in the Western Chongqing block, Sichuan Basin. [PDF]

PLoS One
Fang F, He S, Zhang J, Li X, Zhang H, Chang Y, Li X.   +6 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Evaluating High Ambient Temperature Effects on Milk Production in Local Tunisian Goats: Toward Resilient Breeding Strategies for Arid Environments. [PDF]

Animals (Basel)
Atoui A, Najari S, Ramón M, Díaz C, Abdennebi M, Carabaño MJ.   +5 more
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

The influence of neonatal birth weight on postpartum pelvic floor function in primiparas. [PDF]

Medicine (Baltimore)
Zhou Y, Wu D, Zhu Q, Ling L.
europepmc   +1 more source

TreeGOER Global Zones: Global atlas for the Climatic Moisture Index (CMI), Maximum Climatological Water Deficit (MCWD) and the number of months with average temperature > 10 degrees C (Tmo10)

Roeland Kindt
openalex   +1 more source