Results 61 to 70 of about 745,346 (269)

High-power femtosecond laser generation from an all-fiber linearly polarized chirped pulse amplifier

High Power Laser Science and Engineering, 2023
An all-fiber high-power linearly polarized chirped pulse amplification (CPA) system is experimentally demonstrated. Through stretching the pulse duration to a full width of approximately 2 ns with two cascaded chirped fiber Bragg gratings (CFBGs), a ...
Tao Wang, Can Li, Bo Ren, Kun Guo, Jian Wu, Jinyong Leng, Pu Zhou   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Some bounds on the modified Randic index [PDF]

Kragujevac Journal of Science, 2015
In this paper, we present some new lower and upper bounds for the modified Randic index in terms of maximum, minimum degree, girth, algebraic connectivity, diameter and average distance.
Mahsa Hemmasi, Ali Iranmanesh
doaj   +1 more source

Multiyear variability of the fast ice thickness in the Laptev Sea according to the polar station data

Российская Арктика, 2021
The series of data on the fast ice thickness and the surface air temperature at the Roshydromet land-based polar stations in the Laptev Sea are analyzed. Observations for the last 15-year period (2005-2020) are compared to observations prior to 2004, and
A.B. Timofeeva, M.V. Sharatunova
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Experimental study on heat transfer characteristics of steam underwater direct-contact condensation

Frontiers in Thermal Engineering, 2023
Introduction: The direct-contact condensation (DCC) of steam under water injection is the basic thermodynamic process of the bubble deaerator. In order to understand the complex coupling behavior of strong turbulence and fast phase-change heat transfer ...
Chen Qian, Li Hui, Li Dongyang, Wen Jiming, Li Yong, Xiao Qi, Tan Sichao   +6 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A Local Search Approach for Batch Repair With Configuration Neighbor and Sub-Degree in Circuit System

IEEE Access, 2020
The goal of automated troubleshooting is to diagnose and fix a system by repairing its abnormal behaviors, and this process has wide application. Heuristic search is an efficient way to solve troubleshooting problems, such as the batch repair problem ...
Meng Liu, Dantong Ouyang, Naiyu Tian, Hua Li   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source