Results 151 to 160 of about 2,034,768 (362)
The Dual of the Maximum Likelihood
Open Journal of Statistics, 2016 The Maximum Likelihood method estimates the parameter values of a statistical model that maximizes the corresponding likelihood function, given the sample information. This is the primal approach that, in this paper, is presented as a mathematical programming specification whose solution requires the formulation of a Lagrange problem.
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
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The Maximum Likelihood Data Singular Locus [PDF]
arXiv, 2015 For general data, the number of complex solutions to the likelihood equations is constant and this number is called the (maximum likelihood) ML-degree of the model. In this article, we describe the special locus of data for which the likelihood equations have a solution in the model's singular locus.
arxiv
On the Assumptions Used to Prove Asymptotic Normality of Maximum Likelihood Estimates [PDF]
, 1970 Lucien LeCam
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FEBS Open Bio, EarlyView.Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee +5 more
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A multinomial maximum likelihood program (MUNOML) [PDF]
, 1975 Renwick E. Curry
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FEBS Open Bio, EarlyView.Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu +4 more
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Asymptotic Properties of Maximum Likelihood Estimators for the Independent Not Identically Distributed Case [PDF]
, 1971 Bruce Hoadley
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FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
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FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
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